QuickView for Matrix metalloproteinase-8;jsessionid=C076B53B3AA1BE5F68C9DCB919A587A6;jsessionid=229E34C34E384C8787F0D2B202B7421D (gene)
- Gene Symbol:
- Mmp8
Mus musculus - Full name:
- matrix metallopeptidase 8
- Synonyms:
- BB138268, neutrophil collagenase, collagenase-2, matrix metalloproteinase-8
- Genomic Location:
- Chr 9: 7558460-7568485
- Description:
-
This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme that degrades types ...
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Danio rerio , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
metallopeptidase activity | cation binding | metalloendopeptidase activity | hydrolase activity | catalytic activity | serine hydrolase activity | ion binding | zinc ion binding | serine-type endopeptidase activity | transition metal ion binding | serine-type peptidase activity | calcium ion binding | endopeptidase activity | metal ion binding | peptidase activity
GO Biological Process
metallopeptidase activity | proteolysis | metalloendopeptidase activity | catabolic process | collagen catabolic process | nitrogen compound metabolic process | protein metabolic process | metabolic process | organic substance metabolic process | serine-type endopeptidase activity | serine-type peptidase activity | endopeptidase activity | collagen metabolic process | peptidase activity | macromolecule metabolic process
GO Cellular Component
extracellular matrix | extracellular region | extracellular space
